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 |
Ticker |
Company Name |
Position
Rank |
New/Closed
Postion |
Last
Close |
Value |
Shares Held |
% of
Portfolio |
Value
Change |
Change In
Shares Held |
% of Company |
Industry |
|
BPMC |
Blueprint Medicines Corp |
1 |
- |
$103.63 |
$237,003,000 |
2,498,448 |
6.04% |
-28,793,000 |
-383,119 |
3.785 |
N/A |
|
|
IMCR |
Immunocore Holdings Adr |
2 |
- |
$51.00 |
$153,908,000 |
2,367,816 |
3.92% |
-27,926,000 |
-293,691 |
5.407 |
N/A |
|
|
NBIX |
Neurocrine Biosciences Inc |
3 |
- |
$140.55 |
$145,492,000 |
1,054,900 |
3.71% |
-12,093,000 |
-141,100 |
1.129 |
Biotechnology |
|
|
EVH |
Evolent Health, Inc. |
4 |
- |
$22.98 |
$130,750,000 |
3,987,500 |
3.33% |
-49,000 |
27,500 |
3.016 |
N/A |
|
|
ISRG |
Intuitive Surgical Inc |
5 |
- |
$372.63 |
$119,128,000 |
298,500 |
3.04% |
18,426,000 |
0 |
0.083 |
Medical Appliances & ... |
|
|
UNH |
Unitedhealth Group Inc |
6 |
- |
$523.55 |
$113,781,000 |
230,000 |
2.9% |
-7,307,000 |
0 |
0.024 |
Health Care Plans |
|
|
PEN |
Penumbra Inc |
7 |
- |
$200.23 |
$112,706,000 |
505,000 |
2.87% |
-22,497,000 |
-32,500 |
1.391 |
N/A |
|
|
IDXX |
Idexx Laboratories Inc |
8 |
- |
$518.44 |
$96,782,000 |
179,250 |
2.47% |
-2,711,000 |
0 |
0.21 |
Diagnostic Substances |
|
|
ACHC |
Acadia Healthcare Company Inc |
9 |
- |
$73.18 |
$93,282,000 |
1,177,500 |
2.38% |
9,807,000 |
104,000 |
1.188 |
N/A |
|
|
ARGX |
Argenx Se |
10 |
- |
$356.66 |
$90,260,000 |
229,250 |
2.3% |
3,046,000 |
0 |
0.488 |
N/A |
|
|
BSX |
Boston Scientific Corp |
11 |
- |
$75.67 |
$84,414,000 |
1,232,500 |
2.15% |
13,163,000 |
0 |
0.086 |
Medical Instruments &... |
|
|
RARE |
Ultragenyx Pharmaceutical Inc |
12 |
- |
$40.58 |
$82,872,000 |
1,774,938 |
2.11% |
-1,006,000 |
20,900 |
2.162 |
Restaurants |
|
|
DXCM |
DexCom Inc |
13 |
- |
$130.84 |
$82,769,000 |
596,750 |
2.11% |
8,811,000 |
750 |
0.153 |
Medical Instruments &... |
|
|
LLY |
Eli Lilly & Co |
14 |
- |
$803.17 |
$80,324,000 |
103,250 |
2.05% |
39,811,000 |
33,750 |
0.011 |
Drug Manufacturers - ... |
|
|
FRPT |
Freshpet, Inc. |
15 |
- |
$126.67 |
$76,757,000 |
662,500 |
1.96% |
19,278,000 |
0 |
1.079 |
N/A |
|
|
MDGL |
Madrigal Pharmaceuticals Inc |
16 |
- |
$242.49 |
$76,355,000 |
285,931 |
1.95% |
30,503,000 |
87,762 |
1.448 |
Diagnostic Substances |
|
|
EXAS |
Exact Sciences Corp |
17 |
- |
$53.52 |
$73,186,000 |
1,059,750 |
1.86% |
-2,237,000 |
40,250 |
0.596 |
Biotechnology |
|
|
ALGN |
Align Technology Inc |
18 |
- |
$264.02 |
$72,142,000 |
220,000 |
1.84% |
11,862,000 |
0 |
0.279 |
Medical Appliances & ... |
|
|
RYTM |
Rhythm Pharmaceuticals, Inc. |
19 |
- |
$38.01 |
$65,987,000 |
1,522,893 |
1.68% |
-4,020,000 |
0 |
2.147 |
N/A |
|
|
EW |
Edwards Lifesciences Corp |
20 |
- |
$30.33 |
$61,856,000 |
647,300 |
1.58% |
12,499,000 |
0 |
0.104 |
Medical Appliances & ... |
|
|
KYMR |
Kymera Therapeutics, Inc. |
21 |
- |
$0.00 |
$61,194,000 |
1,522,238 |
1.56% |
22,438,000 |
0 |
2.442 |
N/A |
|
|
CLDX |
Celldex Therapeutics Inc |
22 |
- |
$37.67 |
$57,591,000 |
1,372,185 |
1.47% |
19,135,000 |
402,539 |
2.182 |
Diagnostic Substances |
|
|
PODD |
Insulet Corp |
24 |
- |
$173.42 |
$54,848,000 |
320,000 |
1.4% |
-38,833,000 |
-111,750 |
0.42 |
Medical Instruments &... |
|
|
WST |
West Pharmaceutical Service... |
25 |
- |
$337.01 |
$54,311,000 |
137,250 |
1.38% |
5,983,000 |
0 |
0.186 |
Rubber & Plastics |
|
|
XENE |
Xenon Pharmaceuticals Inc. |
26 |
- |
$0.00 |
$54,053,000 |
1,255,577 |
1.38% |
-3,779,000 |
0 |
1.668 |
N/A |
|
|
AGL |
Agilon Health, Inc. |
27 |
- |
$5.55 |
$53,894,000 |
8,835,000 |
1.37% |
-54,413,000 |
205,000 |
1.885 |
N/A |
|
|
MRUS |
Merus Nv |
28 |
- |
$43.72 |
$51,630,000 |
1,146,560 |
1.32% |
27,648,000 |
274,491 |
1.986 |
N/A |
|
|
AGIO |
Agios Pharmaceuticals Inc |
29 |
- |
$33.88 |
$51,594,000 |
1,764,505 |
1.31% |
3,665,000 |
-387,668 |
2.553 |
N/A |
|
|
HUM |
Humana Inc |
30 |
- |
$355.63 |
$51,109,000 |
147,408 |
1.3% |
-90,812,000 |
-162,592 |
0.111 |
Health Care Plans |
|
|
MIRM |
Mirum Pharmaceuticals, Inc. |
31 |
- |
$0.00 |
$46,637,000 |
1,856,564 |
1.19% |
-8,018,000 |
5,100 |
3.464 |
N/A |
|
|
IRTC |
Irhythm Technologies, Inc. |
32 |
- |
$91.50 |
$45,501,000 |
392,250 |
1.16% |
7,957,000 |
41,500 |
1.117 |
N/A |
|
|
SWAV |
Shockwave Medical, Inc. |
33 |
- |
$329.64 |
$43,960,000 |
135,000 |
1.12% |
21,093,000 |
15,000 |
0.366 |
N/A |
|
|
ASND |
Ascendis Pharma AS |
34 |
- |
$122.85 |
$43,839,000 |
290,000 |
1.12% |
7,313,000 |
0 |
0.449 |
N/A |
|
|
SRPT |
Sarepta Therapeutics Inc |
35 |
- |
$129.12 |
$42,411,000 |
327,600 |
1.08% |
10,821,000 |
0 |
0.389 |
Drug Manufacturers - ... |
|
|
BRKS |
Brooks Automation Inc |
36 |
- |
$51.55 |
$41,880,000 |
694,750 |
1.07% |
8,821,000 |
187,250 |
0.941 |
Semiconductor Equipme... |
|
|
OLK |
Olink Holding Ab Publ Adr |
37 |
- |
$0.00 |
$39,415,000 |
1,676,500 |
1% |
-2,749,000 |
0 |
1.409 |
N/A |
|
|
IMVT |
Immunovant Inc |
38 |
- |
$0.00 |
$37,160,000 |
1,150,123 |
0.95% |
-4,266,000 |
166,822 |
1.321 |
N/A |
|
|
ACCD |
Accolade, Inc. |
39 |
- |
$7.28 |
$37,099,000 |
3,540,000 |
0.95% |
-4,756,000 |
55,000 |
4.971 |
N/A |
|
|
ALNY |
Alnylam Pharmaceuticals Inc |
40 |
- |
$149.62 |
$36,466,000 |
244,000 |
0.93% |
-8,515,000 |
9,000 |
0.198 |
Biotechnology |
|
|
AKRO |
Akero Therapeutics, Inc. |
41 |
- |
$0.00 |
$32,835,000 |
1,299,888 |
0.84% |
7,592,000 |
218,824 |
2.121 |
N/A |
|
|
OSCR |
Oscar Health, Inc. |
42 |
- |
$0.00 |
$31,376,000 |
2,110,000 |
0.8% |
24,651,000 |
1,375,000 |
1.256 |
N/A |
|
|
PCRX |
Pacira Pharmaceuticals, Inc. |
43 |
- |
$30.90 |
$30,842,000 |
1,055,500 |
0.79% |
-4,771,000 |
0 |
2.134 |
Drug Manufacturers - ... |
|
|
RVMD |
Revolution Medicines, Inc. |
44 |
- |
$39.66 |
$29,770,000 |
923,681 |
0.76% |
8,973,000 |
198,529 |
0.564 |
N/A |
|
|
LFST |
Lifestance Health Group, Inc. |
45 |
- |
$7.48 |
$29,493,000 |
4,780,000 |
0.75% |
-6,016,000 |
245,000 |
1.279 |
N/A |
|
|
SGRY |
Surgery Partners, Inc. |
46 |
New |
$25.40 |
$29,383,000 |
985,000 |
0.75% |
29,383,000 |
985,000 |
0.726 |
N/A |
|
|
WRBY |
Warby Parker Inc. |
47 |
- |
$16.90 |
$28,309,000 |
2,080,000 |
0.72% |
-290,000 |
51,700 |
2.168 |
N/A |
|
|
INZY |
Inozyme Pharma, Inc. |
48 |
- |
$0.00 |
$28,198,000 |
3,681,174 |
0.72% |
12,516,000 |
0 |
5.96 |
N/A |
|
|
INSP |
Inspire Medical Systems Inc |
49 |
- |
$152.37 |
$28,030,000 |
130,500 |
0.71% |
7,890,000 |
31,500 |
0.401 |
N/A |
|
|
LEGN |
Churchill Cap Corp Iii |
50 |
- |
$42.96 |
$28,016,000 |
499,486 |
0.71% |
-1,614,000 |
7,042 |
0.386 |
N/A |
|
|
MREO |
Mereo Biopharma Group plc |
51 |
- |
$3.04 |
$26,869,000 |
8,142,109 |
0.68% |
8,426,000 |
158,258 |
7.522 |
N/A |
|
|
TVTX |
Travere Therapeutics, Inc |
52 |
- |
$6.61 |
$26,405,000 |
3,424,818 |
0.67% |
1,490,000 |
653,372 |
3.909 |
N/A |
|
|
CERE |
Cerevel Therapeutics Holdin... |
53 |
- |
$41.77 |
$23,162,000 |
547,946 |
0.59% |
-90,226,000 |
-2,126,299 |
0.351 |
N/A |
|
|
IRON |
Disc Medicine, Inc |
54 |
- |
$31.26 |
$22,630,000 |
363,468 |
0.58% |
1,636,000 |
0 |
1.506 |
N/A |
|
|
COLL |
Collegium Pharmaceutical, Inc |
55 |
- |
$34.50 |
$21,817,000 |
562,000 |
0.56% |
4,519,000 |
0 |
1.354 |
N/A |
|
|
VKTX |
Viking Therapeutics, Inc. |
56 |
New |
$64.23 |
$21,402,000 |
261,000 |
0.55% |
21,402,000 |
261,000 |
0.26 |
N/A |
|
|
DVAX |
Dynavax Technologies Corp |
57 |
- |
$11.46 |
$20,793,000 |
1,675,474 |
0.53% |
-2,630,000 |
0 |
1.243 |
Drug Manufacturers - ... |
|
|
ZLAB |
Zai Lab Ltd |
58 |
- |
$20.01 |
$20,780,000 |
1,297,123 |
0.53% |
-10,295,000 |
160,100 |
1.474 |
N/A |
|
|
MGNX |
Macrogenics Inc |
59 |
- |
$4.26 |
$19,213,000 |
1,305,250 |
0.49% |
7,873,000 |
126,454 |
2.104 |
Biotechnology |
|
|
NVO |
Novo Nordisk A/S (ADR) |
60 |
New |
$135.16 |
$18,939,000 |
147,500 |
0.48% |
18,939,000 |
147,500 |
0.008 |
Drug Manufacturers - ... |
|
|
KRYS |
Krystal Biotech Inc |
61 |
- |
$166.83 |
$18,499,000 |
103,969 |
0.47% |
5,601,000 |
0 |
0.417 |
N/A |
|
|
BCRX |
Biocryst Pharmaceuticals Inc |
62 |
- |
$6.42 |
$17,761,000 |
3,496,256 |
0.45% |
-1,829,000 |
225,875 |
1.845 |
Biotechnology |
|
|
GPCR |
Structure Therapeutics Inc. |
63 |
- |
$35.81 |
$17,686,000 |
412,649 |
0.45% |
6,001,000 |
125,973 |
0.89 |
N/A |
|
|
PHVS |
Pharvaris N V Ord Shs |
64 |
New |
$0.00 |
$17,400,000 |
752,924 |
0.44% |
17,400,000 |
752,924 |
1.818 |
N/A |
|
|
PRTA |
Prothena Corp Plc |
65 |
- |
$21.65 |
$15,482,000 |
625,048 |
0.39% |
-7,232,000 |
0 |
1.164 |
N/A |
|
|
NVRO |
Nevro Corp |
66 |
- |
$9.96 |
$15,379,000 |
1,065,000 |
0.39% |
-6,679,000 |
40,000 |
2.669 |
N/A |
|
|
VERA |
Vera Therapeutics, Inc. |
67 |
New |
$0.00 |
$14,711,000 |
341,168 |
0.37% |
14,711,000 |
341,168 |
0.806 |
N/A |
|
|
MRSN |
Mersana Therapeutics, Inc. |
68 |
- |
$2.62 |
$13,650,000 |
3,046,782 |
0.35% |
6,581,000 |
0 |
2.527 |
N/A |
|
|
FOLD |
Amicus Therapeutics Inc |
69 |
- |
$10.61 |
$13,578,000 |
1,152,656 |
0.35% |
-1,517,000 |
88,850 |
0.339 |
Biotechnology |
|
|
CRNX |
Crinetics Pharmaceuticals, ... |
70 |
New |
$49.50 |
$13,547,000 |
289,400 |
0.35% |
13,547,000 |
289,400 |
0.394 |
N/A |
|
|
CRL |
Charles River Laboratories ... |
71 |
New |
$221.48 |
$13,141,000 |
48,500 |
0.33% |
13,141,000 |
48,500 |
0.091 |
Biotechnology |
|
|
BMRN |
Biomarin Pharmaceutical Inc |
72 |
- |
$88.63 |
$12,999,000 |
148,832 |
0.33% |
-1,351,000 |
0 |
0.079 |
Drug Manufacturers - ... |
|
|
DYN |
Dyne Therapeutics, Inc. |
73 |
New |
$32.63 |
$12,827,000 |
451,824 |
0.33% |
12,827,000 |
451,824 |
0.557 |
N/A |
|
|
JSPR |
Jasper Therapeutics Ord Shs |
74 |
New |
$15.12 |
$11,871,000 |
404,335 |
0.3% |
11,871,000 |
404,335 |
0.398 |
N/A |
|
|
CMPX |
Compass Therapeutics Ord Shs |
75 |
- |
$0.00 |
$10,917,000 |
5,513,788 |
0.28% |
2,315,000 |
0 |
5.625 |
N/A |
|
|
EDAP |
EDAP TMS S.A. (ADR) |
76 |
- |
$6.01 |
$10,841,000 |
1,475,000 |
0.28% |
3,521,000 |
88,575 |
5.062 |
Medical Appliances & ... |
|
|
MLYS |
Mineralys Therapeutics, Inc. |
77 |
- |
$0.00 |
$10,233,000 |
792,615 |
0.26% |
193,000 |
-374,877 |
1.94 |
N/A |
|
|
APLT |
Applied Therapeutics Inc. |
78 |
- |
$0.00 |
$10,186,000 |
1,497,918 |
0.26% |
7,187,000 |
602,723 |
1.94 |
N/A |
|
|
NUVL |
Nuvalent, Inc. |
79 |
New |
$0.00 |
$9,409,000 |
125,302 |
0.24% |
9,409,000 |
125,302 |
0.191 |
N/A |
|
|
ABOS |
Acumen Pharmaceuticals, Inc. |
80 |
- |
$0.00 |
$9,315,000 |
2,300,059 |
0.24% |
483,000 |
0 |
5.683 |
N/A |
|
|
IMTX |
Immatics N.V |
81 |
- |
$10.63 |
$8,920,000 |
848,751 |
0.23% |
-10,829,000 |
-1,026,715 |
1.349 |
N/A |
|
|
NMRA |
Neumora Therapeutics, Inc. |
82 |
New |
$9.45 |
$8,884,000 |
646,118 |
0.23% |
8,884,000 |
646,118 |
0.423 |
N/A |
|
|
ELVN |
Enliven Therapeutics Ord Shs |
83 |
New |
$0.00 |
$7,539,000 |
428,571 |
0.19% |
7,539,000 |
428,571 |
1.04 |
N/A |
|
|
CGON |
CG Oncology, Inc |
84 |
New |
$28.97 |
$7,501,000 |
170,859 |
0.19% |
7,501,000 |
170,859 |
0.259 |
N/A |
|
|
BHVN |
Biohaven Ltd. |
85 |
New |
$38.72 |
$6,945,000 |
126,984 |
0.18% |
6,945,000 |
126,984 |
0.158 |
N/A |
|
|
FULC |
Fulcrum Therapeutics, Inc. |
86 |
- |
$0.00 |
$6,869,000 |
727,673 |
0.18% |
1,957,000 |
0 |
1.155 |
N/A |
|
|
AUTL |
Autolus Therapeutics Plc |
87 |
New |
$3.87 |
$6,590,000 |
1,032,988 |
0.17% |
6,590,000 |
1,032,988 |
0.597 |
N/A |
|
|
LUNG |
Pulmonx Corp |
88 |
- |
$0.00 |
$6,048,000 |
652,400 |
0.15% |
-2,270,000 |
0 |
1.738 |
N/A |
|
|
AUPH |
Aurinia Pharmaceuticals Inc |
89 |
- |
$5.59 |
$5,763,000 |
1,150,347 |
0.15% |
2,054,000 |
737,777 |
0.909 |
N/A |
|
|
EPIX |
ESSA Pharma Inc |
90 |
- |
$0.00 |
$5,748,000 |
677,005 |
0.15% |
1,280,000 |
0 |
1.539 |
Diagnostic Substances |
|
|
PLRX |
Pliant Therapeutics, Inc. |
91 |
- |
$0.00 |
$5,736,000 |
384,996 |
0.15% |
-1,236,000 |
0 |
0.612 |
N/A |
|
|
BEAM |
Beam Therapeutics Inc. |
92 |
- |
$24.80 |
$4,874,000 |
147,510 |
0.12% |
1,841,000 |
36,080 |
0.181 |
N/A |
|
|
VINC |
Vincerx Pharma, Inc |
93 |
- |
$0.72 |
$4,512,000 |
891,719 |
0.11% |
3,460,000 |
0 |
4.242 |
N/A |
|
|
KYTX |
Kyverna Therapeutics |
94 |
New |
$13.70 |
$4,445,000 |
178,963 |
0.11% |
4,445,000 |
178,963 |
0.416 |
N/A |
|
|
SGMT |
Sagimet Biosciences Inc. |
95 |
- |
$4.79 |
$4,177,000 |
770,671 |
0.11% |
175,000 |
32,316 |
3.608 |
N/A |
|
|
GOSS |
Gossamer Bio Inc |
96 |
- |
$0.67 |
$3,855,000 |
3,266,960 |
0.1% |
874,000 |
0 |
1.449 |
N/A |
|
|
ADAP |
Adaptimmune Therapeutics PLC |
97 |
- |
$1.08 |
$3,832,000 |
2,425,468 |
0.1% |
1,909,000 |
0 |
1.568 |
N/A |
|
|
ACRS |
Aclaris Therapeutics, Inc. |
98 |
- |
$1.18 |
$3,414,000 |
2,753,495 |
0.09% |
266,000 |
-245,000 |
3.719 |
N/A |
|
|
CGEN |
Compugen Ltd (USA) |
99 |
- |
$1.86 |
$3,328,000 |
1,289,990 |
0.08% |
774,000 |
0 |
1.557 |
Biotechnology |
|
|
AMLX |
Amylyx Pharmaceuticals, Inc. |
100 |
- |
$0.00 |
$2,872,000 |
1,011,412 |
0.07% |
-5,003,000 |
476,400 |
1.498 |
N/A |
|
|
BMEA |
Biomea Fusion, Inc. |
101 |
- |
$11.58 |
$2,708,000 |
181,147 |
0.07% |
78,000 |
0 |
0.63 |
N/A |
|
